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20 projects from various PSL University member institutions responded to the pre-maturation call for projects. Launched annually, this initiative provides funding for studies, prototypes, proof-of-concept work, and other validations aimed at generating intellectual property and facilitating its transfer to a future startup or an existing company.

After evaluation by independent experts and a selection committee, 10 projects were selected, including 8 funded by the FNV through PSL Valorisation and 2 by the Institut Convergences QLife.


BioPhénol – BPA Substitute

👤 Christophe Thomas
🏫 Institut de Recherche de Chimie Paris: ENSCP-PSL, CNRS
Synthesis of a molecule to replace Bisphenol A (used in dental composites, cosmetics, etc.).

Bunka – LLM Control and Performance

👤 Nicolas Baumard
🏫 Institut Jean Nicod: ENS-PSL, CNRS, EHESS
Software designed to improve exploration, control, and performance of large language models (LLMs), particularly through AI-assisted visual exploration.

GIFT – Genotype/Phenotype Analysis

👤 Andras Paldi
🏫 Centre de Recherche Saint Antoine: EPHE-PSL, INSERM, SU
Algorithm for robust and sensitive genotype/phenotype association studies using limited data, with applications in understanding rare diseases.

MIRE – 3D Imaging

👤 Alexandre Aubry
🏫 Institut Langevin: ESPCI - PSL, CNRS
3D microscopic imaging of living biological tissues with subcellular resolution, offering potential applications in medicine, particularly for embryo selection in in vitro fertilization (IVF).

MOQA * – Human Oocyte Quality Diagnosis

👤 Marie-Emilie Terret
🏫 Centre Interdisciplinaire de Recherche en Biologie: Collège de France, INSERM, CNRS
Diagnostic tool assessing human oocyte quality based on mechanical properties to improve selection in IVF treatments.

PFRO – Water Desalination Solution

👤 Lydéric Bocquet
🏫 LPENS: ENS-PSL, CNRS, SU, Paris Cité
A disruptive reverse osmosis-based water desalination technology that is more efficient and energy-saving than existing processes.
Lydéric Bocquet is the recipient of the CNRS Innovation Medal 2024.

RuCoPOC – Anti-Cancer Drugs

👤 Gilles Gasser
🏫 I-CLeHS: ENSCP-PSL, CNRS
Synthesis of polymers for encapsulating and delivering anti-cancer drug candidates to reduce side effects and enhance treatment effectiveness, particularly for ovarian cancer.

scTCRseq * – Receptor-Antigen Technology

👤 Andrew Griffiths
🏫 Laboratoire Chimie Biologie Innovation: ESPCI-PSL, CNRS
Technology enabling the identification of low-affinity receptor-antigen complexes involved in various immune responses.

Sicklewatch – Sickle Cell Disease Screening

👤 Damien Baigl
🏫 Laboratoire P.A.S.T.E.U.R: ENS-PSL, CNRS, SU
A simple, rapid, and low-cost diagnostic test for sickle cell disease, designed for low-income populations.

TiViDOC – 3D Imaging

👤 Olivier Thouvenin
🏫 Institut Langevin, ESPCI-PSL
A new 3D optical imaging configuration enabling faster and more sensitive acquisition of images of organoids and living biological tissues, particularly the retina.

* Projects funded by the Institut Convergences QLife.