Chemistry of Cell States
In response to their environment, some cells have the ability to adapt and even change function. This ability, known as cellular plasticity, is responsible, for example, for the migration of cancer cells. Yet little is known about the exact mechanisms behind this phenomenon. By combining approaches in chemistry, physical chemistry and biology, the Chemistry of Cell States team will be able to lift the veil on the biological and molecular mechanisms at work in cell plasticity, with the ultimate aim of developing methods for controlling and modelling it. Ultimately, this research should open up a new therapeutic avenue.
The main lines of research
- Improve knowledge of the biological and molecular mechanisms of cellular plasticity
- Develop biological and chemical tools to study cellular plasticity
- Developing molecules to control this cellular plasticity, particularly in the case of certain diseases
- Developing physico-chemical methods for modelling, characterising and quantitatively monitoring changes in the key parameters of cellular plasticity.
Project Leaders
Institut Curie
Ecole Normale Supérieure - PSL
- - PSL
Chimie ParisTech - PSL
ESPCI Paris - PSL
Collège de France
Establishments involved: ​
Institut Curie
Ecole Normale Supérieure - PSL​
EPHE - PSL​
Chimie ParisTech - PSL
ESPCI Paris - PSL